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Teddi Mellencamp Shares Challenges With Immunotherapy Amid Skin Cancer Battle

Reality star Teddi Mellencamp reveals the physical and emotional toll immunotherapy is taking on her body during her ongoing fight against skin cancer, sharing intimate insights with her followers.

Published on20th july 2025
Teddi Mellencamp Shares Challenges With Immunotherapy Amid Skin Cancer Battle
Published: 20th july 2025

Teddi Mellencamp, reality television star and health advocate, has opened up once again about her ongoing battle with stage 2 melanoma, this time sharing that her current immunotherapy treatment is making her feel worse as it intensifies. In a raw and candid update to her followers, the former 'Real Housewives of Beverly Hills' cast member revealed that while she remains hopeful, the treatment has taken a visible and painful toll on her physical health, and the side effects have been harsher than she anticipated. Mellencamp, 42, has been documenting her journey since she was first diagnosed in 2022, when a suspicious mole was removed from her shoulder.

What initially seemed like a routine skin check eventually led to the discovery of multiple melanoma sites across her body. Since then, she’s undergone numerous surgeries, biopsies, and now a challenging round of immunotherapy that is supposed to boost her body’s ability to fight the cancer but comes at a heavy cost. “This is the hardest thing I’ve ever done,” Mellencamp admitted in a recent social media post.

“Immunotherapy is supposed to help your body fight, but right now it feels like it’s fighting me.” Accompanying her post was a photo showing her in a hospital gown, her face pale and visibly fatigued, signaling the seriousness of the situation. Immunotherapy, often used in cases of advanced melanoma, works by stimulating the body’s immune system to recognize and destroy cancer cells. While it can be life-saving, the treatment often comes with severe side effects, including fatigue, nausea, inflammation, and autoimmune reactions.

Mellencamp said she’s experienced most of these, and even a few unexpected complications that have further complicated her care. “There are days I can’t get out of bed. My muscles ache.

I’ve lost my appetite. I wake up drenched in sweat, and I can’t keep food down. It feels like my body is in constant revolt,” she shared.

Despite the pain, Mellencamp has maintained her signature transparency. From sharing images of her surgical scars to providing emotional updates, she’s used her platform to educate others on the importance of early detection and frequent skin checks. “If I can help even one person get a mole looked at or wear sunscreen regularly, then it’s worth it,” she said in a previous interview.

In recent weeks, her messages have taken on a more somber but determined tone, acknowledging the real fear that comes with the diagnosis. “You think you’re strong until something like this hits you. And then you realize strength is just doing the next thing.

Getting up. Going to treatment. Letting your family help you.

Sharing the truth, even when it’s ugly,” Mellencamp said. The mother of three has credited her family—husband Edwin Arroyave and their children—for being her anchor during the hardest parts of treatment. “My kids don’t fully understand what’s happening, and that breaks my heart.

But I try to be there for them, even if it’s from the couch or hospital bed,” she noted. While dealing with the grueling side effects of immunotherapy, Mellencamp is also facing emotional challenges. “There’s a psychological toll to cancer that people don’t always talk about.

The anxiety, the fear, the constant waiting for test results—it never stops,” she wrote. “I used to be such a planner, always controlling every part of my life. But cancer doesn’t care about plans.” Her openness has drawn support from fans and fellow celebrities alike, with many commenting words of encouragement and praising her courage.

Former castmates, including Kyle Richards and Lisa Rinna, have expressed their love and support on social media, calling Mellencamp a “warrior” and “an inspiration.” However, Mellencamp has also made it clear that she’s not interested in sugar-coating her experience. “I don’t want to be called brave just because I’m dealing with this. What choice do I have?” she asked rhetorically.

“I want people to understand the reality of this disease. Not the Instagram version. The real, painful, exhausting truth.” As for what’s next, Mellencamp said her doctors are continuing to monitor her response to immunotherapy.

If the side effects become too dangerous, they may need to adjust or halt treatment. For now, she’s focusing on rest, staying hydrated, and taking things one day at a time. “I don’t know what tomorrow looks like.

But I know I’m still here. I’m still fighting,” she wrote. Her story serves as a powerful reminder of the unseen battles many cancer patients face every day.

From physical agony to mental health struggles, the journey is rarely linear or simple. Teddi’s willingness to reveal both her vulnerabilities and resilience adds depth to the conversation around skin cancer awareness and survivorship. She has also continued to urge fans to be vigilant with their health.

“Get your skin checked. Wear SPF. Trust your instincts.

Don’t wait,” she advised in a recent live Q&A with fans. “If something doesn’t feel right, speak up. I wish I had pushed harder at the beginning, and maybe things would be different.” As Mellencamp’s fight continues, she remains committed to her advocacy, even in the face of uncertainty.

“This isn’t the end of my story,” she said. “It’s just a hard chapter. And I’m going to keep writing it, no matter what it takes.” Her courage, authenticity, and unwavering drive to use her platform for good have already had an undeniable impact.

And as she continues this difficult path, millions are watching—not just as fans, but as fellow travelers in life’s unpredictable and often painful journey..


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